U-GEMMs

Metabolic Targets

SMOC has developed a set of mouse models expressing humanized metabolic targets. These models are suitable to assess the efficacy of drugs targeting metabolic pathways proteins in fully immunocompetent mice.

Mice
Strain Name:C57BL/6Smoc-Apoetm3(hAPOE3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190003
Research Application:Cardiovascular disease
Mice
Strain Name:C57BL/6Smoc-Apoetm2(hAPOE4)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190002
Research Application:Cardiovascular disease
Mice
Strain Name:C57BL/6Smoc-Cidebem1(hCIDEB)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233513
Mice
Strain Name:C57BL/6Smoc-Cyp2dtm(hCYP2D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215016
Mice
Strain Name:C57BL/6Smoc-Cyp2dtm(hCYP2D6)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-215024
Mice
Strain Name:C57BL/6Smoc-Fasem1(hTNFRSF6)/Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-210007
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Fgfr3tm1(hFGFR3-G380R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-232149
Mice
Strain Name:C57BL/6Smoc-Folr1tm(hFOLR1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220418
Mice
Strain Name:C57BL/6Smoc-Gcgrem(hGCGR)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215004
Mice
Strain Name:C57BL/6Smoc-Gcgrem(hGCGR)Glp1rem2(hGLP1R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233747
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