U-GEMMs

Metabolic Targets

SMOC has developed a set of mouse models expressing humanized metabolic targets. These models are suitable to assess the efficacy of drugs targeting metabolic pathways proteins in fully immunocompetent mice.

Mice
Strain Name:C57BL/6Smoc-Giprtm1(hGIPR)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225064
Mice
Strain Name:C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200220
Research Application:Diabetes research; drug screening
Mice
Strain Name:C57BL/6Smoc-Gpr146em1(hGPR146)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-233622
Mice
Strain Name:C57BL/6Smoc-Gpr75em1(hGPR75)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215056
Mice
Strain Name:C57BL/6Smoc-Gucy2ctm(hGUCY2C)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220417
Mice
Strain Name:C57BL/6Smoc-Hao1tm1(hHAO1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-231907
Mice
Strain Name:C57BL/6Smoc-Inhbeem1(hINHBE)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233512
Mice
Strain Name:C57BL/6Smoc-Ldlrtm1(hLDLR)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-230148
Mice
Strain Name:C57BL/6Smoc-Mc4rem1(hMC4R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233876
Mice
Strain Name:C57BL/6Smoc-Mc4rem1(hMC4R-R165W)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233884
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