hGCGR

Nomenclature

C57BL/6Smoc-Gcgrem(hGCGR)Smoc

Cat. NO.

NM-HU-215004

Strain State

Repository Live

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Gene Summary

Gene Symbol
Cxcr5

Model Description

The endogenous mice Gcgr gene was replaced by human GCGR gene.

Validation Data

image.png

Fig1. Detection of GCGR expression in liver by RT-PCR. 

Wild type: only one band at 261 bp with primers F1/R1(mGcgr);Heterozygous: one band at 261 bp with primers F1/R1(mGcgr) and one band at 223 bp with primers F2/R2(hGCGR); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of human GCGR expression in liver in hGCGR knockin mice by IHC. 

Liver were collected from wild-type mice (+/+) and homozygous hGCGR mice (HO/HO), and analyzed by IHC with anti-human GCGR antibody. 


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