U-GEMMs

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

Mice
Strain Name:C57BL/6Smoc-Igs2em1(CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-210145
Research Application:Cancer research
Mice
Strain Name:C57BL/6Smoc-Abcc2tm1(hABCC2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200254
Mice
Strain Name:C57BL/6Smoc-Angpt2tm1(hANGPT2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-200247
Mice
Strain Name:C57BL/6Smoc-Tnfsf13em(hTNFSF13)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220521
Mice
Strain Name:C57BL/6Smoc-Arem1(hAR)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225061
Mice
Strain Name:C57BL/6Smoc-Axltm1(hAXL)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215067
Mice
Strain Name:C57BL/6Smoc-Ccn1em(hCCN1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220518
Mice
Strain Name:C57BL/6Smoc-Ccn2em(hCCN2)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220517
Mice
Strain Name:C57BL/6Smoc-Ccn4tm(hCCN4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220519
Mice
Strain Name:BALB/cAnSmoc-Ccr8em(hCCR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220501
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