EAE animal model
Protocol of inducing
6-8-week-old healthy female C57BL/6 mice were immunized by MOG35-55/CFA on day0.
Validation data
Figure 1: MOG35-55 induced EAE model in C57BL/6 (A) body weight (B) clinical score (n=5).
Figure 2: MOG35-55 induced EAE model in C57BL/6 (A) typical pathology image (B) histological score (n=5), ***P < 0.001 vs G2.
Figure 3: MOG35-55 induced EAE model in C57BL/6 (A) LFB demyelination pathology image (B) LFB score (n=5), *** P < 0.001 vs G2.
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SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.
Learn moreAfter the base is put into operation, SMOC’s capability to provide genetically modified rat/mouse models and technical services including gene function research and drug development will be greatly enhanced.
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