hFOLR1

Nomenclature

C57BL/6Smoc-Folr1tm(hFOLR1)Smoc

Cat. NO.

NM-HU-220418

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Folr1

Synonyms

FBP1; Folbp1; Folbp-1

NCBI ID

14275

MGI ID

95568

Ensembl ID

ENSMUSG00000001827

Pubmed

Folr1

Human Ortholog

FOLR1

Model Description

The endogenous mouse Folr1 gene was replaced by human FOLR1 gene.

Validation Data

image.png

Fig.1 Detection of FOLR1 expression in kidney by RT-PCR. 

Wild type: only one band at 138 bp with primers F1/R1 (mFolr1);

Homozygous: only one band at 133 bp with primers F2/R2 (hFOLR1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human FOLR1 expression in hFOLR1 knockin mice by WB. 

Note. The anti-human FOLR1 antibody cross-reacted with mouse FOLR1 and humanized FOLR1.

Abbr. M, marker; HO, homozygous; WT, wild type.

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