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Nuclear DEK preserves hematopoietic stem cells potential via NCoR1/HDAC3-Akt1/2-mTOR axis

Model Organisms：Mice Product & Service：Pten-Flox Research field：hematopoietic stem cells homeostasis

Published date：2021-03-23 | References：Journal of Experimental Medicine

Pre-existing beta cells but not progenitors contribute to new beta cells in the adult pancreas

Model Organisms：Mouse Product & Service：Ins2-(Kozak-Dre-WPRE-pA) Research field：Diabetes

Published date：2021-03-16 | References：Nat Metab

Chemokine Receptor CCR2b Enhanced Anti-tumor Function of Chimeric Antigen Receptor T Cells Targeting Mesothelin in a Non-small-cell Lung Carcinoma Model

Model Organisms：N/A Product & Service：M-NSG Research field：Lung Carcinoma

Published date：2021-03-11 | References：Front. Immunol

MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche

Model Organisms：Mouse Product & Service：Map3k2-CKO,Rspo1-tdTomato ,Col1a2-CreERT2 Research field：Intestinal

Published date：2021-03-04 | References：Nature

Single-nucleotide methylation specifically represses type I interferon in antiviral innate immunity

Model Organisms：Mice Product & Service：Uhrf1-Flox Research field：viral infection

Published date：2021-03-01 | References：JEM

Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair

Model Organisms：Mouse Product & Service：Mki67-(2A-CreXER2) Research field：lineage tracing

Published date：2021-02-26 | References：SCIENCE

Abnormal Glucose Metabolism in Male Mice Offspring Conceived by in vitro Fertilization and Frozen-Thawed Embryo Transfer

Model Organisms：Mouse Product & Service：/ Research field：In vitro fertilization and embryo transfer (IVF-ET)

Published date：2021-02-09 | References：FRONT CELL DEV BIOL

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting

Model Organisms：Mouse Product & Service：Sox9-IRES-DreERT2;Pdgfb-(DreERT2-IRES-eGFP-wpre-polyA) Research field：lineage tracing

Published date：2021-02-09 | References：CELL STEM CELL

ZFP91 is required for the maintenance of regulatory T cell homeostasis and function

Model Organisms：Mouse Product & Service：Zfp91;Becn1 Research field：T cell

Published date：2021-02-01 | References：J EXP MED

A chimeric antigen receptor with antigen-independent OX40 signaling mediates potent antitumor activity

Model Organisms：Mouse Product & Service：M-NSG Research field：antitumor activity

Published date：2021-01-27 | References：SCI TRANSL MED

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