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Gut microbes exacerbate systemic inflammation and behavior disorders in neurologic disease CADASIL

Model Organisms：Mice Product & Service：Notch3-R170C Research field：CADASIL

Published date：2023-09-08 | References：Microbiome

Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation

Model Organisms：Mice Product & Service：H11-CAG-LSL-Myc Research field：hepatocellular carcinoma

Published date：2023-07-25 | References：Cell Reports

Noncanonical contribution of microglial transcription factor NR4A1 to post-stroke recovery through TNF mRNA destabilization

Model Organisms：Mice Product & Service：Tmem119-2A-CreERT2 Research field：Microglia-mediated neuroinflammation, post-stroke recovery

Published date：2023-07-24 | References：

Generation of Vgll4-DreER transgenic mouse for visualizing and manipulating VGLL4-expressing cells in vivo

Model Organisms：Mice Product & Service：H11-CAG-RSR-tdTomato Research field：Expression profiles of VGLL4 in tissues and organs of mice at different developmental and adult stages

Published date：2023-06-23 | References：JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

A novel Anti-ROS osteoblast-specific delivery system for ankylosing spondylitis treatment via suppression of both inflammation and pathological new bone formation

Model Organisms：Mice Product & Service：Zap70-W163C Research field：Ankylosing Spondylitis

Published date：2023-05-26 | References：Journal of Nanobiotechnology

Breaking Spatiotemporal Barriers of Immunogenic Chemotherapy via an Endoplasmic Reticulum Membrane-Assisted Liposomal Drug Delivery

Model Organisms：Mice Product & Service：huHSC-(M-NSG) Research field：antitumor immunity

Published date：2023-05-19 | References：ACS Nano

Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy

Model Organisms：Mice Product & Service：Acod1-flox Research field：cancer immunotherapy

Published date：2023-04-28 | References：Science Advances

Hu'po Anshen decoction promotes fracture healing in mice with traumatic brain injury through BMP2-COX2-ATF4 signaling pathway

Model Organisms：Mice Product & Service：Col2a1-2A-CreERT2&nbsp Research field：骨损伤

Published date：2023-04-25 | References：FASEB Journal

Ameliorating parkinsonian motor dysfunction by targeting histamine receptors in entopeduncular nucleus–thalamus circuitry

Model Organisms：Mice Product & Service：Slc17a6-IRES-Cre Research field：parkinsonian motor dysfunction

Published date：2023-04-17 | References：PNAS

ANP32B suppresses B-cell acute lymphoblastic leukemia through activation of PU.1 in mice

Model Organisms：Mice Product & Service：Anp32b-Flox Research field：

Published date：2023-04-06 | References：Cancer Science Wiley

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