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Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation

Model Organisms：Mice Product & Service：Rosa26-LSL-MLS-STAT3 Research field：Septicemia

Published date：2022-01-01 | References：Theranostics

Genetic Proliferation Tracing Reveals a Rapid Cell Cycle Withdrawal in Preadolescent Cardiomyocytes

Model Organisms：Mice Product & Service：Ki67-CrexER，Tnnt2-mTnG Research field：Cardiovascular

Published date：2021-12-31 | References：Circulation

A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge

Model Organisms：Mice Product & Service：CAG-hACE2-IRES-Luc-Tg Research field：SARS-CoV-2

Published date：2021-12-14 | References：CELL REP

Reproductive Deficits Induced by Prenatal Antimüllerian Hormone Exposure Require Androgen Receptor in Kisspeptin Cells

Model Organisms：Mice Product & Service：Ar-Flox Research field：Polycystic ovary syndrome

Published date：2021-12-01 | References：

LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity

Model Organisms：Mice Product & Service：Apoe-KO(2) Research field：衰老

Published date：2021-11-23 | References：Cell Reports

A novel role for interleukin 32 in cholestasis

Model Organisms：Mice Product & Service：Abcb4-KO(FVB) Research field：Cholestasis and Gallbladder Disease

Published date：2021-11-23 | References：Clinical and Translational Medicine

Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis

Model Organisms：Mice Product & Service：αSMA-LSL-Dre, Zeb1-LSL-Dre, and R26-CreER Research field：Heart

Published date：2021-11-19 | References：Circulation

Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases

Model Organisms：Mice Product & Service：Tlr2-KO;Cd45.1;Rag2-KO Research field：autoimmune diseases

Published date：2021-11-17 | References：iScience

The oncolytic virus VT09X optimizes immune checkpoint therapy in low immunogenic melanoma

Model Organisms：Mice Product & Service：hPD-1 Research field：Immune checkpoint therapy

Published date：2021-11-12 | References：IMMUNOL LETT

Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle

Model Organisms：Mice Product & Service：Rosa26-DreER ，Ki67-CrexER Research field：Cardiovascular Research

Published date：2021-10-01 | References：Nature Communications

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