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A novel antibody targeting TIM-3 resulting in receptor internalization for cancer immunotherapy

Model Organisms：Mouse Product & Service：TIM-3 Research field：Cancer immunotherapy

Published date：2020-11-09 | References：Antibody Therapeutics

Sca1+ cells minimally contribute to smooth muscle cells in Atherosclerosis

Model Organisms：Mouse Product & Service：Sca1-CreER Research field：Atherosclerosis

Published date：2020-11-04 | References：CIRC RES

Deficiency of STING-signaling in embryonic cerebral cortex leads to neurogenic abnormalities and autistic-like behaviors

Model Organisms：Mouse Product & Service：Tmem173 Research field：Brain function

Published date：2020-11-03 | References：ADV SCI

SQR mediates therapeutic effects of H2S by targeting mitochondrial electron transport to induce mitochondrial uncoupling

Model Organisms：Mouse Product & Service：Sqr Research field：Mitochondria

Published date：2020-09-02 | References：SCI ADV

Germline Mutation of PLCD1 Contributes to Human Multiple Pilomatricomas through Protein Kinase D/Extracellular SignaleRegulated Kinase1/2 Cascade and TRPV6

Model Organisms：Mouse Product & Service：Plcd1-(c.G1186A） Research field：Pilomatricoma

Published date：2020-08-20 | References：J INVEST DERMATOL

Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips

Model Organisms：Mouse Product & Service：Psca-CreERT2 Research field：Prostate

Published date：2020-08-17 | References：NAT GENET

No Evidence for Erythro-Myeloid Progenitor-Derived Vascular Endothelial Cells in Multiple Organs

Model Organisms：Mouse Product & Service：Cd45-iCre Research field：Embryonic development

Published date：2020-08-14 | References：CIRC RES

Interleukin-6 promotes proliferative vitreoretinopathy by inducing epithelial-mesenchymal transition via the JAK1/STAT3 signaling pathway

Model Organisms：Mice Product & Service：Il6-Luc-2A-EGFP Research field：Interleukin-6 promotes proliferative vitreoretinopathy

Published date：2020-07-29 | References：Molecular Vision

Thrombospondin 1 improves hepatic steatosis in diet-induced insulinresistant mice and is associated with hepatic fat content in humans

Model Organisms：Mice Product & Service：CD36-KO Research field：Non-Alcoholic Fatty Liver Disease

Published date：2020-07-21 | References：Elseiver Sciense

Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinery

Model Organisms：Mouse Product & Service：Ndn Research field：Circadian clocks

Published date：2020-07-16 | References：NUCLEIC ACIDS RES

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