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Adipocyte-derived lactate is a signalling metabolite that potentiates adipose macrophage inflammation via targeting PHD2

Model Organisms：Mice Product & Service：Ldha-Flox Research field：Adipose tissue macrophage

Published date：2022-09-05 | References：Nature Communications

SEMA7AR148W mutation promotes lipid accumulation and NAFLD progression via increased localization on the hepatocyte surface

Model Organisms：Mice Product & Service：Sema7a -R148W Research field：NAFLD

Published date：2022-08-08 | References：jci insight

Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis

Model Organisms：Mice Product & Service：Lrat-2A-Cre Research field： NAFLD; NASH

Published date：2022-08-02 | References：Cell Metabolism

T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies

Model Organisms：Mice Product & Service：M-NSG Research field：a selective CAR-T cell therapy

Published date：2022-07-26 | References：nature communications

T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies

Model Organisms：Mice Product & Service：NMG Research field：immune system,CAR-T

Published date：2022-07-26 | References：nature communications

A novel lineage of osteoprogenitor cells with dual epithelial and mesenchymal properties govern maxillofacial bone homeostasis and regeneration after MSFL

Model Organisms：Mice Product & Service：Ctsk-2A-CreERT2; Krt14-2A-DreERT2;Krt14-CreERT2;H11-CAG-LSL-ZsGreen-CAG-RSR-tdTomato Research field：maxillofacial bone homeostasis and regeneration after MSFL

Published date：2022-07-12 | References：Cell Research

Adiponectin/AdiopR1 signaling prevents mitochondrial dysfunction and oxidative injury after traumatic brain injury in a SIRT3 dependent manner

Model Organisms：Mice Product & Service：- Research field：mitochondrial dysfunction and oxidative injury after traumatic brain injury

Published date：2022-06-30 | References：ELSEVIER

A Chimeric Conjugate of Antibody and Programmable DNA Nanoassembly Smartly Activates T cell for Precise Cancer Cell Targeting

Model Organisms：Mice Product & Service：NMG Research field：Immune system

Published date：2022-06-24 | References：A Journal of the Gesellschaft Deutscher Chemiker

Androgens drive sexual dimorphism in liver metastasis by promoting hepatic accumulation of neutrophils

Model Organisms：Mice Product & Service：Ar-Flox,Rag2-KO Research field：liver metastasis

Published date：2022-06-21 | References：Cell Reports

JAML promotes acute kidney injury mainly through a macrophage-dependent mechanism

Model Organisms：Mice Product & Service：Jaml-KO Research field：acute kidney injury

Published date：2022-06-16 | References：JCI Insight

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