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U-GEMMs

Immunodeficient

Immunodeficient models have contributed to major scientific advances in xenografting (PDX, CDX), oncology, stem cell studies (ES/iPS), hematopoietic and immunological studies, and pharmacodynamic studies.

Mice
hKITLG(NMG)
Strain Name：NOD-PrkdcscidIl2rgem1Kitlem1(hKITLG)/Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000039
Research Application：Immunotherapy,drug screening
Mice
Hr-KO（NMG)
Strain Name：NOD-PrkdcscidIl2rgem1Hrem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-NSG-021
Mice
huHSC-(NMG)
Strain Name：huHSC-(NMG)
Strain State：Repository Live | Cat. NO.：NM-NSG-017
Research Application：Infectious disease; Gene therapy; Cancer; Drug targets without cross-reactivity; Immunogenicity study
Mice
huPBMC-(NMG)
Strain Name：huPBMC-(NMG)
Strain State：Repository Live | Cat. NO.：NM-NSG-015
Research Application：Infectious disease; Gene therapy;Hematopoiesis; Drug targets without cross-reactivity; Immunogenicity study
Mice
Kit-V831M(NOD-scid)
Strain Name：NOD-PrkdcscidKitem1(V831M)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200316
Research Application：Hematopoieticstem cell
Mice
MHC Class II (I-A/I-E) -KO
Strain Name：C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18032
Research Application：immune system
Mice
MHC Class II(I-A/I-E)-KO(Nod-Scid)
Strain Name：NOD-PrkdcscidH2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-psem1Smoc
Strain State：Developing | Cat. NO.：NM-KO-18057
Research Application：immune system
Mice
MHC ClassII(I-A/I-E)-KO(NMG)
Strain Name：NOD-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1Smoc
Strain State：Developing | Cat. NO.：NM-NSG-003
Research Application：immunodeficiency,immune system,transplantation research
Mice
MHCII/B2m-KO(NMG)
Strain Name：NOD.Cg-PrkdcscidIl2rgem1SmocH2-Ab1em1SmocH2-Aaem1SmocH2-Eb1em1SmocH2-Eb2em1SmocH2-Ea-psem1SmocB2mem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-014
Research Application：Immunodeficiency, immune system, transplantation research
Mice
MHCII/B2M-KO/hFCGRT(NMG)
Strain Name：NOD-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-psem1B2mem1Fcgrt(B2m-FCGRT)/Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-018
Research Application：Antibody drug metabolism; drug screening
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