hAPRIL

Nomenclature

C57BL/6Smoc-Tnfsf13em(hTNFSF13)Smoc

Cat. NO.

NM-HU-220521

Strain State

Repository Live

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Gene Summary

Gene Symbol

Synonyms

2310026N09Rik APRIL TALL2 TRDL1

NCBI ID

69583

MGI ID

1916833

Ensembl ID

ENSMUSG00000089669

Pubmed

Human Ortholog

TNFSF13

Model Description

The endogenous mouse Tnfsf13 gene was replaced by human TNFSF13 gene.

Validation Data

image.png

Fig.1 Detection of TNFSF13 expression in lung by RT-PCR. 

Wild type: only one band at 180 bp with primers F1/R1 (mTnfsf13);

Homozygous: only one band at 217 bp with primers F2/R2 (hTNFSF13).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hTNFSF13 expression on CD11b- cells in Peripheral blood and Bone marrow in hAPRIL mice.

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Fig.3 Detection of hTNFSF13 expression on CD11b+ cells in Peripheral blood and Bone marrow in hAPRIL mice.

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