hIL6/hIL6R(NMG)

Nomenclature

NOD-PrkdcscidIl2rgem1Il6tm(hIL6)Il6raem(hIL6R)Smoc

Cat. NO.

NM-HU-220427

Strain State

Repository Live

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Model Description

The hIL6/hIL6R (NM-HU-190025) mice were backcrossed to NMG genetic background, to create the new strain of hIL6/hIL6R(NMG) (NM-HU-220427) mice.

Validation Data

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Fig.1 Detection of hIL-6 expression in serum by ELISA in hIL6/hIL6R(NMG) mice (n=3). 

Abbr. HO, homozygous; WT, wild type. 

Note. hIL6/hIL6R(NMG) and NMG mice were i.p. injected with LPS for 2h.

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Fig 2. Detection of hIL-6R expression on Myeloid cells in spleen in hIL6/hIL6R(NMG) mice.

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Fig 3. Detection of hIL-6R expression on Myeloid cells in peripheral blood  in hIL6/hIL6R(NMG) mice.

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