SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：BALB/cAnSmoc-Cd40em(hCD40)Cd40lgtm(hCD40LG)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220563
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Strain Name：C57BL/6Smoc-Cd40em(hCD40)Tnfrsf4em(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220645
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Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210406
Research Application：inmmue therapy; drug screening
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Strain Name：C57BL/6Smoc-Cd40lgtm1(hCD40L)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000033
Research Application：Immunotherapy,drug screening
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Strain Name：BALB/cAnSmoc-Cd40lgtm1(hCD40L)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000052
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Cd44em(hCD44)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215003
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Strain Name：C57BL/6Smoc-Cd5tm(hCD5)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220579
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Strain Name：C57BL/6Smoc-Cd52em1(hCD52)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000058
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Cd55tm(hCD55)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215008
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Strain Name：C57BL/6Smoc-Cd6em(hCD6)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220210
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