hCD44

Nomenclature

C57BL/6Smoc-Cd44em(hCD44)Smoc

Cat. NO.

NM-HU-215003

Strain State

Embryo cryopreservation

Export PDF

Gene Summary

Gene Symbol
Cxcr5

Synonyms

Blr1; Gpcr6; MDR15; CXC-R5; CXCR-5

NCBI ID

12145

MGI ID

103567

Ensembl ID

ENSMUSG00000047880

Pubmed

Cxcr5

Human Ortholog

CXCR5

Model Description

The endogenous mice Cd44 gene was replaced by human CD44 gene.

Validation Data

image.png


Fig1. Detection of CD44 expression in spleen and lung by RT-PCR. Wild type: only one band at 213 bp with primers F1/R1(mCd44);Heterozygous: one band at 213 bp with primers F1/R1(mCd44) and one band at 442 bp with primers F2/R2(hCD44); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Expression characterization of hCD44 on MOLM-16 cell line.

image.png

Fig3. Expression characterization of hCD44 in Blood in hCD44 KI mice.

image.png

Fig4. Expression characterization of hCD44 in Spleen in hCD44 KI mice.

image.png

Fig5. Expression characterization of hCD44 in Bone Marrow in hCD44 KI mice.

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more