U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Smad3tm1(hSMAD3)Smoc
Strain State:Developing | Cat. NO.:NM-HU-232900
Mice
Strain Name:C57BL/6Smoc-Smn1tm1(hSMN2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234022
Mice
Strain Name:C57BL/6Smoc-Sncatm(hSNCA)Smoc
Strain State:Developing | Cat. NO.:NM-HU-220261
Mice
Strain Name:C57BL/6Smoc-Sod1tm1(hSOD1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225056
Mice
Strain Name:C57BL/6Smoc-Sort1em1(hSORT1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225035
Mice
Strain Name:C57BL/6Smoc-Sostem1(hSOST)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200251
Mice
Strain Name:C57BL/6Smoc-Sostem1(hSOST)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215021
Mice
Strain Name:C57BL/6Smoc-Spnem1(hSPN)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225032
Mice
Strain Name:C57BL/6Smoc-Spp1tm1(hSPP1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225037
Mice
Strain Name:C57BL/6Smoc-Stab1tm1(hSTAB1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234593
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