U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:BALB/cAnSmoc-Siglec15em2(hSIGLEC15) Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200001
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Sigleceem1(hSIGLEC8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-204983
Research Application:Immunotherapy, drug screening
Mice
Strain Name:C57BL/6Smoc-Siglecfem1(hSIGLEC8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210033
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Sigleceem1(hSIGLEC9)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225072
Mice
Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18015
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000111
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Ctla4em1(hCTLA4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210368
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47) Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000090
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210358
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220029
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