U-GEMMs

Cytokines

SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice. 

Mice
Strain Name:C57BL/6Smoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200275
Mice
Strain Name:BALB/cAnSmoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220018
Mice
Strain Name:C57BL/6Smoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210415
Mice
Strain Name:C57BL/6Smoc-Il2rgem1(IL2RG)Il2tm3(hIL2)Il2rbtm1(hIL2RB)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220145
Mice
Strain Name:C57BL/6Smoc-Il21tm1(hIL21)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200255
Mice
Strain Name:C57BL/6Smoc-Il21tm1(hIL21)Il21rtm1(hIL21R)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220038
Mice
Strain Name:C57BL/6Smoc-Il23aem3(hIL23A)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-18030
Research Application:Immunotherapy,Cancer research,Drug screening
Mice
Strain Name:BALB/cAnSmoc-Il23aem3(hIL23A)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220013
Mice
Strain Name:C57BL/6Smoc-Il3tm1(hIL3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190009
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190065
Research Application:Immunotherapy,cancer research,drug screening
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