SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Il3tm1(hIL3)Csf2tm1(CSF2)Csf1tm2(CSF1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200271
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Strain Name：C57BL/6Smoc-Il31em2(IL31)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200008
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Il33tm2(hIL33)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000069
Research Application：Cytokine humanization model；drug screening
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Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190071
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：NOD-PrkdcscidIl2rgem2Tg(hIL4)Smoc
Strain State：Developing | Cat. NO.：NM-KI-220132
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Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000106
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Il4tm3(hIL4)Il4ratm1(hIL4RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220167
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Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190001
Research Application：Immune-related
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Strain Name：NOD-PrkdcscidIl2rgem2Tg(hIL5)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220131
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Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5raem2(hIL5RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220010
Research Application：Immunotherapy,cancer research,drug screening
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