Avp-IRES-Cre

Nomenclature

C57BL/6Smoc-Avpem1(IRES2-Cre-WPRE-polyA)Smoc

Cat. NO.

NM-KI-200142

Strain State

Repository Live

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Gene Summary

Gene Symbol
Avp

Synonyms

Vp; Vsp

NCBI ID

11998

MGI ID

88121

Ensembl ID

ENSMUSG00000037727

Pubmed

Avp

Human Ortholog

AVP

Model Description

A IRES2-Cre-WPRE-polyA expression cassette was knocked into the Avp gene stop codon site. Avp encodes arginine vasopressin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying hypertension.
Research Application：Cre recombinase tool; Neuroscience

Validation Data

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Fig. 1 Cre-mediated recombination in the brain of AvpCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the suprachiasmatic nucleus (SCN) of AvpCre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of AvpCre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in some cells of the brian, kidney, intestine, colon, eyes, brown fat, testis, epididymis, salivary gland, stomach, thymus, liver, pancreas, muscle, spleen and heart. (For more detailed information please contact our technical advisor.)


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