Calb2-IRES-Cre

Nomenclature

C57BL/6Smoc-Calb2em1(IRES-iCre-SV40-pA)Smoc

Cat. NO.

NM-KI-200102

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Calb2

Synonyms

CR

NCBI ID

12308

MGI ID

101914

Ensembl ID

ENSMUSG00000003657

Pubmed

Calb2

Human Ortholog

CALB2

Model Description

A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system.
Research Application：Cre recombinase tool

Validation Data

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Fig. 1 Cre-mediated recombination in the pituitary gland of Calb2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the hippocampus, cortex, olfactory bulb and cerebellar purkinje cells of Calb2Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of  Calb2Cre/+; Rosa26tdTomato/+ mice. Tdtomato expression can be detected in the brain, heart, lung, liver, stomach, kidney, pancreas, intestine, testis, epididymis, spleen, esophagus, thymus and colon.  (For more detailed information please contact our technical advisor.)


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