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U-GEMMs

About 42,537 results
Mice

CD8a-IRES-Luc-2A-tdTomato（BALB/c）

Strain Name：BALB/cAnSmoc-CD8aem5(IRES-Akaluc-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200208

A IRES-luci-2A-tdTomato expression cassette was knocked into the CD8a gene stop codon site.

Mice

hCCR2

Strain Name：C57BL/6Smoc-Ccr2em2(hCCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18026

The endogenous mouse Ccr2 gene was replaced by human CCR2 gene.

Mice

Mefv-hMEFV*V726A

Strain Name：C57BL/6Smoc-Mefvem1(hMEFV-V726A)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200221

Exon 7-10 of the endogenous mouse Mefv gene was replaced by human mutation gene (exon7-10).

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

hVEGFR2

Strain Name：C57BL/6Smoc-Kdrtm2(hKDR) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00098

The endogenous mouse Kdr gene was replaced by human KDR gene .

Mice

hBTLA(2)

Strain Name：C57BL/6Smoc-Btlaem2(hBTLA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190040

Extracellular domain of mouse Btla gene was replaced by human BTLA gene. While hBTLA mice(Stock No.NM-HU-18014）have been pulled from shelves for some reasons.

Mice

hTTR

Strain Name：C57BL/6Smoc-Ttrtm1(hTTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225087

The endogenous mouse Ttr gene was replaced by human TTR gene.

Mice

hC5

Strain Name：C57BL/6Smoc-Hcem1(hC5)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000013

The endogenous mouse C5a gene was replaced by human C5 gene.

Mice

h4-1BB(2)/hCD3E(2)

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Cd3eem2(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210409

h4-1BB(2)(NM-HU-190077) was crossed with hCD3E(2)(NM-HU-210023)to generate h4-1BB(2)/hCD3E(2) mice.

Mice

hCD40(BALB/c)

Strain Name：BALB/cAnSmoc-Cd40em1(hCD40)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000047

The endogenous mouse Cd40 gene was replaced by human CD40 gene.

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