hIFNGR1

Nomenclature

C57BL/6Smoc-Ifngr1tm(hIFNGR1)Smoc

Cat. NO.

NM-HU-190076

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
IFNGR1

Model Description

The endogenous mouse Ifngr1 gene was replaced by human IFNGR1 gene.
Research Application:Immunotherapy,Cancer research,Drug screening

Validation Data

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Fig1. Detection of IFNGR1 expression by RT-PCR. Wild type: only one band at 271 bp with primers F2/R2(mIfngr1);Homozygous: only one band at 296 bp with primers F1/R1(hIFNGR1); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Validation of hCD119(IFNGR1) expression in blood by FACS. 

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Fig3. Validation of hCD119(IFNGR1) expression in spleen by FACS. 

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Fig4. Validation of hCD119(IFNGR1) expression in bone marrow by FACS. 


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