MC38-hCD47

Export PDF

Strain Information

Cell Line

MC38-Cd47em1(hCD47)/Smoc

Cat. NO.

NM-S13-TM05

Model Description

The endogenous mouse Cd47 gene was replaced by human CD47 gene.

Strain State

Validation of pharmacodynamic assays completed

Validation Data

image.png

Figure 1. hCD47 expression in wild-type MC38 and MC38-hCD47 cell lines.

image.png

Figure 2. Tumor growth curve of MC38-hCD47 syngeneic model (n=5).

image.png

Figure 3. Body weight change of MC38-hCD47 syngeneic model (n=5).

image.png

Figure 4. The expression of hCD47 in humanized modified tumors by FACS.

image.png

Figure 5. Antitumor activity of antibody (n=8).

Related Strain(s)

MC38-hCD47-hGPC3-Tg
Cell Line：

MC38-hCD47-hGPC3-Tg

Cat. NO.：NMC-230092
WEHI 164-hCD47
Cell Line：

WEHI 164-hCD47

Cat. NO.：NMC-230077
Hepa 1-6-hCD47
Cell Line：

Hepa 1-6-hCD47

Cat. NO.：NMC-230083
MC38-hCD47-hCLDN18.2-hB7H3
Cell Line：

MC38-hCD47-hCLDN18.2-hB7H3

Cat. NO.：NM-S13-TM71
MC38-hCD47-hCLDN18.2-hB7H4
Cell Line：

MC38-hCD47-hCLDN18.2-hB7H4

Cat. NO.：NM-S13-TM72

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more