MC38-hHER3

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Strain Information

Cell Line

MC38-Igs2em1(hHER3)Smoc

Cat. NO.

NM-S13-TM49

Model Description

A HER3 expression cassette was knocked into the H11 locus.

Strain State

Validation of tumorigenic capacity completed

Validation Data

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Fig1. hHER3 expression on in vitro cultured cells of MC38-hHER3.

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Fig2. In vivo validation of MC38-hHER3 in C57BL/6 mice.

C57BL/6 mice were inoculated with MC38-hHER3 subcutaneously at 1×106 cells/mouse inoculum for tumor development.

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Fig3. hHER3 expression in tumors after in vivo growth of MC38-hHER3 in wild type C57BL/6 mice.

The tumors were collected at day 33 post tumor cell inoculation.

Related Strain(s)

MC38-hCD47/hCLDN18.2/hHER3
Cell Line：MC38-CD47em1(hCD47)Cldn18.2em2(hCLDN18.2)Her3em3(hHER3)Smoc
Cat. NO.：NMC-230043

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