MC38-hFOLR1

Export PDF

Strain Information

Cell Line

MC38-Igs2em1(FOLR1)Smoc

Cat. NO.

NM-S13-TM43

Model Description

A FOLR1 expression cassette was knocked into the H11 locus.

Strain State

Validation of tumorigenic capacity completed

Validation Data

image.png

Fig1. hFOLR1 expression in in vitro cultured cells of MC38-hFOLR1.

image.png

Fig2. In vivo validation of MC38-hFOLR1 in C57BL/6 mice. C57BL/6 mice were inoculated with MC38-hFOLR1 subcutaneously at 1×106 cells/mouse inoculum for tumor development.Note: MC38-hFOLR1 (clone #8) is recommended for in vivo studies.

image.png

Fig3. hFOLR1 expression in tumors after in vivo growth of MC38-hFOLR1 in wild type C57BL/6 mice. The tumors were collected at day 22 post tumor cell inoculation.

image.png

Fig4. hFOLR1 expression in tumors after in vivo growth of MC38-hFOLR1 in wild type C57BL/6 mice. The tumors were collected at day 26 post tumor cell inoculation.

Related Strain(s)

CT26-Rosa26-hFOLR1/hCD47
Cell Line：CT26-Gt(ROSA)26Sorem1(hFOLR1/hCD47)Smoc
Cat. NO.：NMC-230025
MC38-hFOLR1/hCD47(2)
Cell Line：

MC38-Igs2em(hFOLR1)Cd47tm(hCD47)Smoc

Cat. NO.：NM-S13-TM87

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more