LKB1-KO/Kras-G12D-Luc

Export PDF

Strain Information

Cell Line

LKB1-KO/Kras-G12D-Luc

Cat. NO.

NM-YD07

Model Description

derived from LKB1-KO/Kras-G12D-Luc mice spontaneous lung cancer model

Strain State

Validation of tumorigenic capacity completed

Validation Data

image.png

Fig1. The genotype of LKB1-KO/Kras-G12D-Luc cell was identified by PCR

WT: wild-type cells; H2O: negative water control; 100bp DNA marker from Transgen(BM311)

image.png

Fig2. Tumor growth curve in LKB1-KO/Kras-G12D-Luc subcutaneously transplanted tumor model (n=6)  

image.png

Fig3. Body weight change in LKB1-KO/Kras-G12D-Luc subcutaneously transplanted tumor model (n=6)

image.png

Fig4. Signal increase curve of LKB1-KO/Kras-G12D-Luc cells were implanted orthotopically in the lung (n=6)

image.png

Fig5. Body weight change in orthotopically injected LKB1-KO/Kras-G12D-Luc model (n=6)

image.png

Fig6. Survival curve of LKB1-KO/Kras-G12D-Luc orthotopic model (n=6)

image.png

Fig7. Bioluminescence imaging of LKB1-KO/Kras-G12D-Luc subcutaneously transplanted tumor model at different timepoints

image.png

Fig8. Bioluminescence imaging of LKB1-KO/Kras-G12D-Luc orthotopic model (n=6)

Related Strain(s)

HepG2-Luc
Cell Line：

HepG2-Tg(luc)/Smoc

Cat. NO.：NM-G02-1
KrasG12D/Mki67-e(2A-tdtomato-2A-AKaluciferase)
Cell Line：

KrasG12D/Mki67-e(2A-tdtomato-2A-AKaluciferase)

Cat. NO.：NM-YD10
hHER2*ex20ins-IRES-Luc-2A-EGFP
Cell Line：

hHER2*ex20ins-IRES-Luc-2A-EGFP

Cat. NO.：NM-YD09
B16F10-hGPC3-Luc-Tg
Cell Line：B16F10-hGPC3-Luc-Tg
Cat. NO.：NMC-230091
Huh-7-Luc
Cell Line：

Huh-7-Luc

Cat. NO.：NM-G03-1

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more