F8-KO(SD)
Nomenclature
SD-F8em1Smoc
Cat. NO.
NR-KO-200003
Strain State
Repository Live
Gene Summary
Model Description
Using CRISPR/Cas9 technology, exon 16 of F8 gene was deleted to generate F8 knockout rat.
Research Application：Hemophilia A;HEMA
*Literature published using this strain should indicate: F8-KO(SD) rats (Cat. NO. NR-KO-200003) were purchased from Shanghai Model Organisms Center, Inc..
Validation Data
Fig1. APTT test of F8-KO(SD).
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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