Zfyve26-KO

Nomenclature

C57BL/6Smoc-Zfyve26em1Smoc

Cat. NO.

NM-KO-201099

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Zfyve26

Synonyms

Gm893， mKIAA0321， 4930465A13， 9330197E15Rik， A630028O16Rik

NCBI ID

211978

MGI ID

1924767

Ensembl ID

ENSMUSG00000066440

Pubmed

Zfyve26

Human Ortholog

ZFYVE26

Model Description

Exon 3 of Zfyve26 gene was deleted to generate Zfyve26 knockout mice.

Disease Connection

Hereditary Spastic Paraplegia 15

Phenotype(s)

MGI:5749268

Reference(s)

Khundadze M, Kollmann K, Koch N, Biskup C, Nietzsche S, Zimmer G, Hennings JC, Huebner AK, Symmank J, Jahic A, Ilina EI, Karle K, Schols L, Kessels M, Braulke T, Qualmann B, Kurth I, Beetz C, Hubner CA, A hereditary spastic paraplegia mouse model supports a role of ZFYVE26/SPASTIZIN for the endolysosomal system. PLoS Genet. 2013;9(12):e1003988

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