H11-CAG-LSL-hACHE
Nomenclature
C57BL/6Smoc-Igs2em1(CAG-LSL-ACHE-WPRE-pA)Smoc
Cat. NO.
NM-KI-00067
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Model Description
These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven ACHE gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. ACHE is expressed when bred to mice that express Cre recombinase.
Research Application：Cholinesterase related drug research
*Literature published using this strain should indicate: H11-CAG-LSL-hACHE mice (Cat. NO. NM-KI-00067) were purchased from Shanghai Model Organisms Center, Inc..
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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