Ywhaz-KO

Nomenclature

C57BL/6Smoc-Ywhazem1Smoc

Cat. NO.

NM-KO-202154

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Ywhaz

Synonyms

AI596267， AL022924， AU020854， 14-3-3zeta， 1110013I11Rik

NCBI ID

22631

MGI ID

109484

Ensembl ID

ENSMUSG00000022285

Pubmed

Ywhaz

Human Ortholog

YWHAZ

Model Description

Exon 4 of Ywhaz gene was deleted to generate Ywhaz knockout mice.

Disease Connection

Schizophrenia

Phenotype(s)

MGI:5762957

Reference(s)

Cheah PS, Ramshaw HS, Thomas PQ, Toyo-Oka K, Xu X, Martin S, Coyle P, Guthridge MA, Stomski F, van den Buuse M, Wynshaw-Boris A, Lopez AF, Schwarz QP, Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3zeta deficiency. Mol Psychiatry. 2012 Apr;17(4):451-66

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