Nrg3-KO

Nomenclature

C57BL/6Smoc-Nrg3em1Smoc

Cat. NO.

NM-KO-201022

Strain State

Embryo cryopreservation

Export PDF

Gene Summary

Gene Symbol
Nrg3

Synonyms

ska

NCBI ID

18183

MGI ID

1097165

Ensembl ID

ENSMUSG00000041014

Pubmed

Nrg3

Human Ortholog

NRG3

Model Description

Exon 3 of Nrg3 gene was deleted to generate Nrg3 knockout mice.

Disease Connection

Schizophrenia

Phenotype(s)

MGI:6283412

Reference(s)

Hayes LN, Shevelkin A, Zeledon M, Steel G, Chen PL, Obie C, Pulver A, Avramopoulos D, Valle D, Sawa A, Pletnikov MV, Neuregulin 3 Knockout Mice Exhibit Behaviors Consistent with Psychotic Disorders. Mol Neuropsychiatry. 2016 Jul;2(2):79-87

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more