B2m-KO
Nomenclature
C57BL/6Smoc-B2mem3Smoc
Cat. NO.
NM-KO-18021
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
B2M
Model Description
Validation Data
Fig1 . There are few CD8+ cytotoxic T-cells and increase in CD4+ T-cells in B2M knockout mice. Immune responses involving CD8+T-cells are severely deficient providing a model to assess the role of CD8+ cells and class I MHC in various experimental systems.
Publications
Disruption of palladin results in neural tube closure defects in mice
References：Mol Cell Neurosci
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreOur vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
Learn more
