B2m-KO

Nomenclature

C57BL/6Smoc-B2mem3Smoc

Cat. NO.

NM-KO-18021

Strain State

Repository Live

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Gene Summary

Official Symbol
B2M

Model Description

Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.
Research Application:immune system

Validation Data

b2m流式.png

Fig1 . There are few CD8+ cytotoxic T-cells and increase in CD4+ T-cells in B2M knockout mice. Immune responses involving CD8+T-cells are severely deficient providing a model to assess the role of CD8+ cells and class I MHC in various experimental systems. 


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