hSIRPA(2)/hCD47
Nomenclature
C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)/Smoc
Cat. NO.
NM-HU-2000111
Strain State
Repository Live
Gene Summary
Gene Symbol
SIRPA
Gene Symbol
CD47
Gene Symbol
CD47
Model Description
This SIRPA and CD47 double Knock-in strain is established by crossing hSIRPA and hCD47 mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.While hSIRPA/hCD47 (Stock No.NM-HU-190019) have been pulled from shelves for some reasons.
Validation Data
Fig 1. Detection of m&hCD47 expression on T, B, NK cells in HO hSIRPA(2)/hCD47 mice.
Fig 2. Detection of m&hCD47 expression on erythrocytes and platelets in HO hSIRPA(2)/hCD47 mice.
Fig 3. Detection of m&hCD47 expression in PB sample in HO hSIRPA(2)/hCD47 mice.
Fig 4. Detection of m&hCD47 expression in spleen sample in HO hSIRPA(2)/hCD47 mice.
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