hICOS(2)
Nomenclature
C57BL/6Smoc-Icosem2(hICOS)Smoc
Cat. NO.
NM-HU-190030
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
ICOS
Model Description
The endogenous mouse Icos gene was replaced by human ICOS gene. While hICOS(Stock No.NM-HU-00052) mice function similarly to hICOS(2) mice,for more detailed information please contact our technical advisor.
Research Application：Immunotherapy,cancer research,drug screening
*Literature published using this strain should indicate: hICOS(2) mice (Cat. NO. NM-HU-190030) were purchased from Shanghai Model Organisms Center, Inc..
Validation Data
Fig1. Detection of hICOS expression on splenocyte-derived activated T cells in hICOS KI mice.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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