hLAG3/hCTLA-4
Nomenclature
B6.129S-Lag3tm1(hLAG3)Ctla4em1(hCTLA4)/Smoc
Cat. NO.
NM-HU-190018
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
CTLA4
Gene Symbol
LAG3
Model Description
This LAG3 and CTLA4 double knockin strain is established by crossing LAG3-HU and CTLA4-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
Research Application：Immune-related
*Literature published using this strain should indicate: hLAG3/hCTLA-4 mice (Cat. NO. NM-HU-190018) were purchased from Shanghai Model Organisms Center, Inc..
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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