hHLA-A2*01

Nomenclature

C57BL/6Smoc-H2-D1em1hHLA-A2*01Smoc

Cat. NO.

NM-KI-233927

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
H2-D1

Synonyms

H-2D; H2-D; H2-K1

NCBI ID

14964

MGI ID

95896

Ensembl ID

ENSMUSG00000073411

Pubmed

H2-D1

Human Ortholog

HLA-A，HLA-B，HLA-C

Gene Symbol
H2-D1

Synonyms

H-2D H2-D H2-K1

NCBI ID

14964

MGI ID

95896

Ensembl ID

ENSMUSG00000073411

Pubmed

H2-D1

Human Ortholog

H2-D1

Model Description

The endogenous mouse H2-D1 gene was replaced by human HLA-A2*01 gene .

Validation Data

image.png

Fig.1 Detection of mH-2D and HLA-A2 expression on overall Leukocytes in hHLA-A2.01 dKI mice (female, 6-8wks).

image.png

Fig.2 Analysis of leukocytes cell subpopulation in HO hHLA-A2.01 and WT C57BL/6 mice (female, 6-8wks, n=3).

image.pngFig.3 Analysis of leukocytes cell subpopulation in Spleen (female, 6-8wks).

image.pngFig.4 Analysis of leukocytes cell subpopulation in Blood (female, 6-8wks).

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more