U-GEMMs

Immune Checkpoints

SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice. 

Mice
Strain Name:C57BL/6Smoc-Slamf7em(hSLAMF7)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18028
Research Application:Immunotherapy,Cancer research,Drug screening
Mice
Strain Name:C57BL/6Smoc-Tmem173tm2(hTMEM173)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190036
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:BALB/cAnSmoc-tmem173tm1(htmem173)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000049
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00053
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Tigittm3(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200244
Mice
Strain Name:BALB/cAnSmoc-Tigittm4(hTIGIT)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200245
Mice
Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Ccr8em1(hCCR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210426
Mice
Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Pvrem1(hPVR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000091
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Tigittm3(hTIGIT)Tnfrsf1bem2(hTNFRSF1B)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210371
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Havcr2em1(hHAVCR2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00054
Research Application:Immunotherapy,cancer research,drug screening
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