4T1-hCD47

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Strain Information

Cell Line

4T1-Cd47em1(hCD47)Smoc

Cat. NO.

NM-S07-TM02

Model Description

The endogenous mouse Cd47 gene was replaced by human CD47 gene.

Strain State

Validation of tumorigenic capacity completed

Validation Data

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Fig1. hCD47 expression on in vitro cultured cells of 4T1-hCD47. (In collaboration with CrownBio)

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Fig2. In vivo validation of 4T1-hCD47 in hSIRPA/hCD47 (BALB/c) mice. (In collaboration with CrownBio) hSIRPA/hCD47 Balb/C mice were inoculated subcutaneously with 4T1 at 3×105 and 4T1-hCD47 at 3×106 cells/mouse inoculum for tumor development.

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Fig3. hCD47 expression in tumors after in vivo growth of 4T1-hCD47 in hSIRPA/hCD47(BALB/c) mice. (In collaboration with CrownBio) The tumors were collected at day 35 and day 40 post tumor cell inoculation.

Related Strain(s)

MC38-hCD47-hGPC3-Tg
Cell Line：

MC38-hCD47-hGPC3-Tg

Cat. NO.：NMC-230092
WEHI 164-hCD47
Cell Line：

WEHI 164-hCD47

Cat. NO.：NMC-230077
Hepa 1-6-hCD47
Cell Line：

Hepa 1-6-hCD47

Cat. NO.：NMC-230083
MC38-hCD47-hCLDN18.2-hB7H3
Cell Line：

MC38-hCD47-hCLDN18.2-hB7H3

Cat. NO.：NM-S13-TM71
MC38-hCD47-hCLDN18.2-hB7H4
Cell Line：

MC38-hCD47-hCLDN18.2-hB7H4

Cat. NO.：NM-S13-TM72

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