U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Visrem1(hVSIR)Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000092
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00062
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em2(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190039
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em2(hPD-L1)Ccr8em1(hCCR8)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210401
Mice
Strain Name:C57BL/6Smoc-Cd274em2(hPD-L1)Cd28em2(hCD28)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210370
Research Application:inmmue therapy;drug screening
Mice
Strain Name:BALB/cAnSmoc-Cd274em(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220028
Mice
Strain Name:BALB/cAnSmoc-Cd274em2(hPD-L1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230474
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Tnfrsf9tm2(h4-1BB)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200260
Research Application:umor research;inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd27tm3(hCD27)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200274
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Cd28em2(hCD28)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210019
Research Application:tumor research;inmmue therapy;drug screening
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