hCCL1

Nomenclature

C57BL/6Smoc-Ccl1em2(hCCL1)/Smoc

Cat. NO.

NM-HU-2000074

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ccl1

Model Description

The endogenous mouse Ccl1 gene was replaced by human CCL1 gene.

Research Application:Immunotherapy,drug screening

Validation Data

image.png

Fig.1 Detection of CCL1 expression in thymus by RT-PCR. 

Wild type: only one band at 197 bp with primers F1/R1(mCcl1);

Homozygous: only one band at 194 bp with primers F2/R2(hCCL1).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hCCL1 and mCCL1 expression in serum by ELISA (6-8wks, female, n=3). 

Abbr. HO, homozygous; WT, wild type.

Note. hCCL1 and C57BL/6 mice were i.p. injected with con.A for 3h.


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