hTL1A(BALB/c)
Nomenclature
BALB/cAnSmoc-Tnfsf15em1(hTNFSF15)Smoc
Cat. NO.
NM-HU-220602
Strain State
Repository Live
Gene Summary
Gene Symbol
Tnfsf15
Model Description
The endogenous mouse Tnfsf15 gene was replaced by human TNFSF15 gene.
Validation Data
Fig.1 Detection of TL1A expression in bladder by RT-PCR.
Wild type: only one band at 285 bp with primers F1/R1 (mTl1a);
Homozygous: only one band at 233 bp with primers F2/R2 (hTL1A).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of hTL1A (A) and mTL1A (B) expression in lung homogenate by ELISA (n=3).
Abbr. HO, homozygous;WT, wild type.
Note. hTL1A and BALB/c mice were i.p. injected with LPS for 6h. The anti-human and mouse TL1A kit cross-reacted with mTL1A and humanized TL1A.
Fig.3 Detection of TL1A expression on endothelial and epithelial cells in lung in hTL1A mice
Note. The hom hTL1A mice were stimulated with LPS in vivo.
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