Il1a-Luc-2A-EGFP

Nomenclature

C57BL/6Smoc-Il1aem1(Luc-eGFP)Smoc

Cat. NO.

NM-KI-00009

Strain State

Embryo cryopreservation

Export PDF

Gene Summary

Gene Symbol
Il1a

Synonyms

Il-1a

NCBI ID

16175

MGI ID

96542

Ensembl ID

ENSMUSG00000027399

Pubmed

Il1a

Human Ortholog

IL1A

Model Description

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. According to this strategy, the endogenous Il1a expression is supposed to be eliminated and the intrisic promoter drives the expression of reporter genes, which reflexs the activity of Il1a.
Research Application：Inflammation and immunity, gene tracing

Validation Data

image.png

Fig1. Individual fluorescence intensity of Il1a-Luc-2A-EGFP mice treated with LPS.

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more