hC1R

Nomenclature

C57BL/6Smoc-C1raem1(hC1R)/Smoc

Cat. NO.

NM-HU-2000075

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
C1ra

Model Description

The endogenous mouse C1ra gene was replaced by human C1R gene.
Research Application:Immunotherapy,drug screening

Validation Data

image.png

Fig1. Detection of C1R expression in bladder and liver by RT-PCR. 

Wild type: only one band at 443 bp with primers F1/R1(mC1r);

Homozygous: only one band at 174 bp with primers F2/R2(hC1R); 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of hC1R expression in serum by ELISA (n=6). 

Abbr. HO, homozygous; WT, wild type.


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