hC5
Nomenclature
C57BL/6Smoc-Hcem1(hC5)Smoc
Cat. NO.
NM-HU-2000013
Strain State
Repository Live
Gene Summary
Gene Symbol
Model Description
Validation Data
Fig 1. Detection of C5 expression by RT-PCR.
Wild type: only one band at 167 bp with primers F2/R2(mC5);
Homozygous: only one band at 337 bp with primers F1/R1(hC5).
Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig 2. Analysis of humanized C5 and humanized C5a expression in serum in the humanized C5 mouse by ELISA.
The homozygous hC5 KI mice were treated with LPS or NS (3mg/kg, i.p.) for 6 hours.
Fig 3. Detection of hC5 expression in eyes in hC5 KI mice by IF (n=3/group).
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