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U-GEMMs

About 42,207 results
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hCCR2

모델명：C57BL/6Smoc-Ccr2em2(hCCR2)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-18026

The endogenous mouse Ccr2 gene was replaced by human CCR2 gene.

마우스

H11-CAG-LSL-Myc

모델명：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

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h4-1BB(2)/hCD3E(2)

모델명：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Cd3eem2(hCD3E)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-210409

h4-1BB(2)(NM-HU-190077) was crossed with hCD3E(2)(NM-HU-210023)to generate h4-1BB(2)/hCD3E(2) mice.

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Pten-KO

모델명：C57BL/6Smoc-Ptenem3Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-KO-18002

Exon5 of Pten gene was deleted to generate Pten knockout mice.

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Ccr2-2A-DreERT2

모델명：C57BL/6Smoc-Ccr2em3(2A-DreERT2)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200023

A 2A-DreERT2 expression cassette was knocked into the Ccr2 gene stop codon site.

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hCD3E

모델명：C57BL/6Smoc-Cd3eem1(hCD3E) Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-00114

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.

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hCD28

모델명：C57BL/6Smoc-Cd28em2(hCD28)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-190011

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

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Rag2/IL2rg-KO/hCD40

모델명：C57BL/6Smoc-Cd40em1(hCD40)Rag2em1Il2rgem1/Smoc
모델 상태：Developing | 카탈로그：NM-HU-2000112

The Rag2 and Il2rg genes of the CD40 humanized mouse were deleted.

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hCD38(2)

모델명：C57BL/6Smoc-Cd38em2(CD38)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-190059

The endogenous mouse Cd38 gene was replaced by human CD38 gene. While hCD38 mice(Stock No.NM-HU-00113）have been pulled from shelves for some reasons.

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hCD19

모델명：C57BL/6Smoc-Cd19em1(hCD19) Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-HU-00110

The endogenous mouse Cd19 gene was replaced by human CD19 gene .

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