SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd19em1(hCD19) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220109
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Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Ms4a1tm2 (hCD20) /Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220119
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Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd28em2(hCD28) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220113
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Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd28em2(hCD28)Cd38em2(hCD38) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220115
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Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd38em2(hCD38) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220114
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Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd40em1(hCD40) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220116
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Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd40em1(hCD40)Tnfrsf9tm2(TNFRSF9) /Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220117
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Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd47em1(hCD47) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220127
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Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Epcamtm1(hEPCAM) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220123
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Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd274em1(hPD-L1) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220112
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