Tmem119-2A-CreERT2
Nomenclature
C57BL/6Smoc-Tmem119em2(P2A-CreERT2)Smoc
Cat. NO.
NM-KI-200234
Strain State
Repository Live
Gene Summary
Gene Symbol
Tmem119
Model Description
A P2A-CreERT2 expression cassette was knocked into the Tmem119 gene stop codon site.
Validation Data
Fig1. Tmem119-CreERT2 mice effectively recombine a conditional allele in microglia.
A-B. Confocal micrograph showing tdTomato expression in IBA-positive microglia upon tamoxifen administration , Absence of tdTomato expression in untreated animals. C-D, Representative immunostaining for astrocytes (C, GFAP, green), and neurons (D, NeuN, green) in tdTomato-expressing microglia of Tmem119-CreERT2+/−; Rosa26 tdTomato+/− mice.
Publications
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