Krt5-IRES-CreERT2

Nomenclature

C57BL/6Smoc-Krt5em1(IRES-CreERT2)Smoc

Cat. NO.

NM-KI-200168

Strain State

Repository Live

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Gene Summary

Gene Symbol
Krt5

Model Description

A IRES-CreERT2 expression cassette was knocked into the Krt5 gene stop codon site.
Research Application:Cre recombinase tool

Validation Data

Krt5-IRES-CreERT2-1 - 副本.png

Fig. 1 Detection of tdTomato (red) in the epidermis and hair follicle of Krt5CreERT2/+; Rosa26tdTomato/+  mouse. CreERT2-mediated recombination in the epidermis and hair follicle of Krt5CreERT2/+; Rosa26tdTomato/+ mouse. Some leakiness were detected in the epidermis and hair follicle prior to tamoxifen exposure.

Krt5-IRES-CreERT2-2 - 副本.png

Fig. 2 Detection of tdTomato (red) in various tissues of Krt5CreERT2/+; Rosa26tdTomato/+ mice. 

CreERT2-mediated recombination in the brown fat and submandibular gland can be induced by tamoxifen. Some leakiness were detected in the skin,eyes and testis prior to tamoxifen exposure.


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